Description

3-[3-Hydroxy-4-(Methoxy-D3)Phenyl]-2-Propenoic Acid is a deuterated derivative of ferulic acid, a naturally occurring phenolic compound. This deuterium-labeled analog is of significant value for research and development, particularly in the fields of analytical chemistry and pharmacology. It serves as a critical stable isotope-labeled internal standard for mass spectrometry, enabling precise quantification and metabolic studies. Industries such as pharmaceutical development, contract research organizations (CROs), and advanced material science rely on this high-purity compound for its consistency and reliability in sensitive analytical applications.

Application

• Internal Standard for LC-MS/MS Analysis: Used as a deuterated internal standard for the accurate quantification of ferulic acid and its metabolites in complex biological matrices like plasma, serum, and tissue homogenates.
• Pharmacokinetic and Metabolic Studies: Essential in drug development for tracing the absorption, distribution, metabolism, and excretion (ADME) of phenolic compounds and related drug candidates.
• Biomarker Research: Facilitates the development and validation of robust analytical methods for biomarker discovery related to oxidative stress and inflammation.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and method validation in pharmaceutical laboratories.
• Isotope Dilution Mass Spectrometry (IDMS): Employed in high-precision analytical techniques to achieve superior accuracy and minimize matrix effects in quantitative analysis.
• Nutraceutical and Cosmetic Ingredient Analysis: Used to assay ferulic acid content and stability in finished products like anti-aging serums, supplements, and functional foods.

Basic Information

Item	Detail
Product Name	3-[3-Hydroxy-4-(Methoxy-D3)Phenyl]-2-Propenoic Acid
CAS No.	1028203-97-5
Molecular Formula	C10H7D3O4
Molecular Weight	197.20 g/mol
Synonyms	Ferulic Acid-d3; (E)-3-(4-(Methoxy-d3)-3-hydroxyphenyl)acrylic Acid; 4-Hydroxy-3-(methoxy-d3)cinnamic Acid; 3-(4-(Methoxy-d3)-3-hydroxyphenyl)-2-propenoic Acid; Deuterated Ferulic Acid; trans-Ferulic Acid-d3; Coniferic Acid-d3; FA-d3
EINECS	Contact for details

Quality Control

Our 3-[3-Hydroxy-4-(Methoxy-D3)Phenyl]-2-Propenoic Acid is manufactured under strict quality systems to ensure the high purity and isotopic enrichment required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and impurity profile. We adhere to relevant industry standards for reference materials, and our rigorous quality testing includes advanced chromatographic and spectroscopic methods to guarantee batch-to-batch consistency and reliability for your most sensitive assays.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is light-sensitive (store away from light). For long-term storage, consider storing desiccated under inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.