Description

3-(4-Methylpiperazin-1-Yl)-1H-Indazol-5-Amine CAS NO 1027258-20-3 is a high-purity, heterocyclic organic compound featuring a fused indazole core substituted with a methylpiperazine moiety. This specific molecular architecture makes it a critical intermediate and building block in advanced pharmaceutical research and development. It is primarily sought after by pharmaceutical companies and contract research organizations (CROs) engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, particularly in oncology and CNS research.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and optimizing potent kinase inhibitors due to its privileged heterocyclic structure.
• Chemical Biology Research: Used as a molecular probe or tool compound to study biological pathways and protein-ligand interactions.
• Custom Synthesis Building Block: Employed in medicinal chemistry for the parallel and combinatorial synthesis of novel chemical libraries.
• Active Pharmaceutical Ingredient (API) Development: Integral in the research phase for developing new candidate drug molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for GMP and non-GMP scale-up projects.

Basic Information

Product Name	3-(4-Methylpiperazin-1-Yl)-1H-Indazol-5-Amine
CAS No.	1027258-20-3
Molecular Formula	C12H17N5
Molecular Weight	231.30 g/mol
Synonyms	5-Amino-3-(4-methyl-1-piperazinyl)-1H-indazole; 1H-Indazol-5-amine, 3-(4-methyl-1-piperazinyl)-; 3-(4-Methylpiperazin-1-yl)-1H-indazol-5-amine; 1027258-20-3; 5-Amino-3-(4-methylpiperazin-1-yl)-1H-indazole; 3-(4-Methyl-1-piperazinyl)-1H-indazol-5-amine; 3-(4-Methylpiperazino)-1H-indazol-5-amine
EINECS	Contact for details

Quality Control

Our 3-(4-Methylpiperazin-1-Yl)-1H-Indazol-5-Amine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. All batches are supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ISO 9001 quality management principles, and material can be supplied to meet specific customer protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.