Description

Methyl 3-Amino-5-(3,3-Dimethylbut-1-Ynyl)Thiophene-2-Carboxylate is a high-purity, functionalized thiophene derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines an electron-rich thiophene core with a reactive amino group and a sterically hindered alkyne moiety, enabling precise chemical modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the construction of novel heterocyclic compounds, active pharmaceutical ingredients (APIs), and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring complex heterocycles.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the thiophene scaffold contributes to biological activity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of conductive polymers, organic semiconductors, and advanced organic electronic materials.
• Chemical Synthesis: Employed as a versatile building block for Suzuki, Sonogashira, and other cross-coupling reactions to create complex molecular architectures.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized dyes and pigments with specific optical properties.
• Academic & Contract Research: Essential for methodological development and exploratory chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Item	Details
Product Name	Methyl 3-Amino-5-(3,3-Dimethylbut-1-Ynyl)Thiophene-2-Carboxylate
CAS No.	1026785-75-0
Molecular Formula	C12H15NO2S
Molecular Weight	237.32 g/mol
Synonyms	Methyl 3-amino-5-(3,3-dimethyl-1-butyn-1-yl)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 3-amino-5-(3,3-dimethyl-1-butyn-1-yl)-, methyl ester; 3-Amino-5-(3,3-dimethylbut-1-yn-1-yl)thiophene-2-carboxylic acid methyl ester; Methyl 3-amino-5-(3,3-dimethylbut-1-ynyl)thiophene-2-carboxylate; 1026785-75-0; Tert-butylacetylene thiophene derivative
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Amino-5-(3,3-Dimethylbut-1-Ynyl)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.