Description

5-(3,3-Dimethylbut-1-yn-1-yl)-3-(N-(4-hydroxycyclohexyl)-4-methylcyclohexanecarboxamido)thiophene-2-carboxylic acid is a sophisticated, high-purity organic compound featuring a thiophene carboxylic acid core with strategically substituted cyclohexyl and alkyne moieties. This complex molecular architecture makes it a valuable advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

This specialized intermediate is designed for high-value synthesis in regulated industries. Its primary applications include:

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for exploratory drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic compounds.
• Biochemical Research: Serves as a precursor or reference standard in biochemical assays and pharmacological studies.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom production of complex molecules for clients.
• Process Development: Used in the development and scale-up of synthetic routes for new chemical entities under Good Manufacturing Practice (GMP) conditions where applicable.

Basic Information

Product Name	5-(3,3-Dimethylbut-1-yn-1-yl)-3-(N-(4-hydroxycyclohexyl)-4-methylcyclohexanecarboxamido)thiophene-2-carboxylic acid
CAS No.	1026785-55-6
Molecular Formula	C25H35NO4S
Molecular Weight	445.62 g/mol
Synonyms	5-(3,3-Dimethyl-1-butynyl)-3-[[(trans-4-hydroxycyclohexyl)amino]carbonyl]-4-methyl-2-thiophenecarboxylic acid; 3-[(4-Hydroxycyclohexyl)carbamoyl]-5-(3,3-dimethylbut-1-yn-1-yl)-4-methylthiophene-2-carboxylic acid; Thiophene-2-carboxylic acid, 5-(3,3-dimethyl-1-butyn-1-yl)-3-[[(4-hydroxycyclohexyl)amino]carbonyl]-4-methyl-; 1026785-55-6; BDBM50164957; AKOS025147065; FT-0775786; STK562759
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to stringent quality protocols. Certificates of Analysis (COA) are provided with each batch, detailing purity and impurity profiles. Quality is assured through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. While typically supplied as a research-grade material, production can be aligned with ICH guidelines for stability and impurity profiling to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from light exposure to maintain stability and purity. For long-term storage, consider desiccants and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.