Description

6-Iodo-5-Methyl 1H-Indole is a halogenated indole derivative, a versatile and high-value building block in advanced organic synthesis. Its unique structure, featuring both iodine and methyl substituents on the indole core, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in oncology and CNS (Central Nervous System) research.
• Agrochemical Development: Used to create advanced fungicides, herbicides, and plant growth regulators with enhanced efficacy.
• Material Science Research: Serves as a building block for organic semiconductors, OLED (Organic Light-Emitting Diode) materials, and photochromic compounds.
• Cross-Coupling Reactions: The iodine atom is an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) to create complex biaryl and conjugated systems.
• Chemical Biology Probes: Utilized in the development of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Academic & R&D: A valuable reagent for methodological studies in synthetic organic chemistry and heterocyclic chemistry.

Basic Information

Product Name	6-Iodo-5-Methyl 1H-Indole
CAS No.	1026581-42-9
Molecular Formula	C9H8IN
Molecular Weight	257.07 g/mol
Synonyms	5-Methyl-6-iodo-1H-indole; 6-Iodo-5-methylindole; 1H-Indole, 6-iodo-5-methyl-; 5-Methyl-6-iodindol; 6-Iodo-5-methyl-1H-indole
EINECS	Contact for details

Quality Control

Our 6-Iodo-5-Methyl 1H-Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.