Description

Methyl 3-Amino-5-Chlorobenzo[B]Thiophene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate (API intermediate) with significant synthetic utility. This compound serves as a critical building block in the synthesis of complex heterocyclic molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides due to its bioactive benzo[b]thiophene core.
• Material Science Research: Acts as a monomer or building block for creating specialized polymers and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex heterocyclic dyes and organic pigments.
• Chemical Biology Probes: Useful for creating labeled compounds and probes for biochemical and pharmacological research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	Methyl 3-Amino-5-Chlorobenzo[B]Thiophene-2-Carboxylate
CAS No.	1026241-99-5
Molecular Formula	C10H8ClNO2S
Molecular Weight	241.69 g/mol
Synonyms	Methyl 3-amino-5-chlorobenzo[b]thiophene-2-carboxylate; 3-Amino-5-chlorobenzo[b]thiophene-2-carboxylic acid methyl ester; 5-Chloro-3-aminobenzo[b]thiophene-2-carboxylic acid methyl ester; Methyl 5-chloro-3-aminobenzo[b]thiophene-2-carboxylate; 2-Carbomethoxy-3-amino-5-chlorobenzo[b]thiophene; 1026241-99-5; Benzo[b]thiophene-2-carboxylic acid, 3-amino-5-chloro-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-5-Chlorobenzo[B]Thiophene-2-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, GC, and NMR, to meet exacting customer specifications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.