Description

n-(4-(2-(6,7-Dimethoxy-3,4-Dihydroisoquinolin-2(1H)-Yl)Ethyl)Phenyl)Nicotinamide is a high-purity, synthetic organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on neurology, cardiology, and metabolic disease research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting specific receptors.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic and receptor-binding assays.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Preclinical Development: Supplied in development quantities for pharmacokinetic and toxicology studies.
• Academic Research: Utilized in university and institutional labs for fundamental pharmacological research.
• Custom Synthesis: Starting material for the tailored synthesis of more complex, proprietary molecules.

Basic Information

Product Name	n-(4-(2-(6,7-Dimethoxy-3,4-Dihydroisoquinolin-2(1H)-Yl)Ethyl)Phenyl)Nicotinamide
CAS No.	1024592-65-1
Molecular Formula	C25H27N3O3
Molecular Weight	417.50 g/mol
Synonyms	N-[4-[2-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]phenyl]pyridine-3-carboxamide; 1024592-65-1; Nicotinamide, N-[4-[2-(6,7-dimethoxy-3,4-dihydro-2(1H)-isoquinolyl)ethyl]phenyl]-; UNII-8K1F8Q8Q4H; 8K1F8Q8Q4H; BDBM50388811; CHEMBL3185147; AKOS025147324; ZINC000004169756
EINECS	Contact for details

Quality Control

Our n-(4-(2-(6,7-Dimethoxy-3,4-Dihydroisoquinolin-2(1H)-Yl)Ethyl)Phenyl)Nicotinamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and regulatory compliance, supporting its use in critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.