Description

2-Thiophenecarboxylic Acid, 5-[3-(Trifluoromethyl)Phenyl]-, Methyl Ester is a high-value, specialized organic compound featuring a thiophene core linked to a trifluoromethylphenyl group. This unique structure makes it a critical advanced intermediate for the synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients. The compound's design offers a versatile scaffold for introducing specific functional groups essential for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the thiophene and trifluoromethyl motifs contribute to efficacy and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Ligand Synthesis: Utilized for constructing complex ligands in catalysis and coordination chemistry.
• Chemical Biology Probe Development: Acts as a core structure for creating molecular probes to study biological pathways and protein function.

Basic Information

Product Name	2-Thiophenecarboxylic Acid, 5-[3-(Trifluoromethyl)Phenyl]-, Methyl Ester
CAS No.	1024448-98-3
Molecular Formula	C13H9F3O2S
Molecular Weight	286.27 g/mol
Synonyms	Methyl 5-[3-(trifluoromethyl)phenyl]thiophene-2-carboxylate; 5-(3-Trifluoromethylphenyl)thiophene-2-carboxylic Acid Methyl Ester; 2-Thiophenecarboxylic acid, 5-[3-(trifluoromethyl)phenyl]-, methyl ester; Methyl 5-(3-(trifluoromethyl)phenyl)thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of our 2-Thiophenecarboxylic Acid, 5-[3-(Trifluoromethyl)Phenyl]-, Methyl Ester is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.