Description

3-Amino-4-Methyl-Thieno[2,3-B]Pyridine-2-Carboxylic Acid Methyl Ester is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its critical role in the synthesis of complex molecules, particularly in medicinal chemistry for drug discovery and development. It is primarily needed by research institutions and pharmaceutical companies engaged in creating novel therapeutic agents, especially those targeting kinase inhibition and other biological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for investigational drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: Used in the research and development of potential kinase inhibitors due to its privileged thienopyridine core structure.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to create more complex heterocyclic systems for agrochemical and material science applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	3-Amino-4-Methyl-Thieno[2,3-B]Pyridine-2-Carboxylic Acid Methyl Ester
CAS No.	1024388-72-4
Molecular Formula	C11H10N2O2S
Molecular Weight	234.27 g/mol
Synonyms	Methyl 3-amino-4-methylthieno[2,3-b]pyridine-2-carboxylate; 3-Amino-4-methylthieno[2,3-b]pyridine-2-carboxylic acid methyl ester; Thieno[2,3-b]pyridine-2-carboxylic acid, 3-amino-4-methyl-, methyl ester; 1024388-72-4; 3-Amino-4-methyl-thieno[2,3-b]pyridine-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Methyl-Thieno[2,3-B]Pyridine-2-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.