Description

(S)-Ethyl 2-(6-Hydroxy-2,3-Dihydrobenzo[B]Thiophen-3-Yl)Acetate is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for the development of complex, biologically active molecules, particularly in pharmaceutical research. This compound is essential for R&D chemists and process development scientists working in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for their synthetic pathways.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides, where the specific stereochemistry can significantly influence biological activity and environmental safety.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrance and flavor compounds that require specific stereochemical configurations.
• Academic and Industrial R&D: A valuable tool for method development in organic chemistry, exploring new synthetic routes and catalytic transformations.
• Material Science Research: Potential precursor for the synthesis of functionalized organic materials and liquid crystals where the benzo[b]thiophene core is incorporated.

Basic Information

Product Name	(S)-Ethyl 2-(6-Hydroxy-2,3-Dihydrobenzo[B]Thiophen-3-Yl)Acetate
CAS No.	1022979-99-2
Molecular Formula	C₁₄H₁₆O₃S
Molecular Weight	264.34 g/mol
Synonyms	(S)-Ethyl 2-(6-Hydroxy-2,3-dihydrobenzo[b]thiophen-3-yl)acetate; (3S)-3-(2-Ethoxy-2-oxoethyl)-2,3-dihydro-6-hydroxy-1-benzothiophene; 6-Hydroxy-2,3-dihydrobenzo[b]thiophen-3-ylacetic Acid Ethyl Ester, (S)-; (S)-Ethyl (6-hydroxy-2,3-dihydro-1-benzothiophen-3-yl)acetate; (S)-3-(Carbethoxymethyl)-6-hydroxy-2,3-dihydrobenzo[b]thiophene; (S)-6-Hydroxy-2,3-dihydrobenzo[b]thiophene-3-acetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our (S)-Ethyl 2-(6-Hydroxy-2,3-Dihydrobenzo[B]Thiophen-3-Yl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which could affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.