Description

2-Ethyl-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly within the central nervous system (CNS) therapeutic area. It is primarily sought after by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in the development of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of complex drug molecules, especially those targeting neurological disorders.
• Organic Synthesis Building Block: Used in research and development for constructing novel heterocyclic compounds and exploring new chemical entities.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule synthesis.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	2-Ethyl-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid
CAS No.	1022919-86-3
Molecular Formula	C₁₂H₁₅NO₂
Molecular Weight	205.25 g/mol
Synonyms	2-Ethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 3-Isoquinolinecarboxylic acid, 2-ethyl-1,2,3,4-tetrahydro-; 2-Ethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 2-Ethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 1022919-86-3; UNII-8Q4Q5F8Q0K; 8Q4Q5F8Q0K; SCHEMBL21806227; DTXSID60664619
EINECS	Contact for details

Quality Control

Our 2-Ethyl-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO standards ensures a reliable supply of material suitable for advanced pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.