Description

4-Hydroxy-3-[(2E)-3-(4-Methoxyphenyl)Prop-2-Enoyl]-2H-Chromen-2-One is a specialized coumarin derivative that serves as a critical intermediate in advanced organic synthesis. Its unique molecular structure, featuring a chalcone moiety fused to a coumarin core, makes it a valuable building block for developing novel compounds with targeted biological activities. This high-purity intermediate is essential for research and development laboratories in the pharmaceutical and agrochemical sectors, where it is used to create new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and metabolic disorders.
• Agrochemical Research: Used in developing new generation pesticides and herbicides, leveraging its bioactive coumarin scaffold.
• Organic Light-Emitting Diodes (OLEDs): Acts as a functional material in the research of organic electronic devices due to its fluorescent properties.
• Dye & Pigment Intermediate: Serves as a building block for synthesizing specialized dyes and optical brighteners.
• Biochemical Probe Development: Utilized in academic and industrial research to create molecular probes for studying enzyme activity and cellular processes.
• Material Science: Investigated for use in polymer chemistry and as a component in advanced functional materials.

Basic Information

Product Name	4-Hydroxy-3-[(2E)-3-(4-Methoxyphenyl)Prop-2-Enoyl]-2H-Chromen-2-One
CAS No.	1022282-99-0
Molecular Formula	C19H14O5
Molecular Weight	322.31 g/mol
Synonyms	4-Hydroxy-3-(3-(4-methoxyphenyl)acryloyl)-2H-chromen-2-one; 3-Cinnamoyl-4-hydroxycoumarin (4-Methoxy Derivative); (2E)-3-(4-Methoxyphenyl)-1-(4-hydroxy-2-oxo-2H-chromen-3-yl)prop-2-en-1-one; 4-Methoxyphenylcoumarinyl Chalcone; 4-Hydroxy-3-[(1E)-3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]-2H-1-benzopyran-2-one; 1022282-99-0; 4-Hydroxy-3-(3-(4-methoxyphenyl)prop-2-enoyl)chromen-2-one
EINECS	Contact for details

Quality Control

Every batch of 4-Hydroxy-3-[(2E)-3-(4-Methoxyphenyl)Prop-2-Enoyl]-2H-Chromen-2-One is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.