Description

3-Amino-5-tert-Butyl-2-Nitro-Thiophene is a high-value, functionalized heterocyclic building block essential for advanced organic synthesis. Its unique molecular architecture, featuring both electron-donating amino and electron-withdrawing nitro groups on a thiophene scaffold, makes it a critical intermediate for developing novel materials and active compounds. This product is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides that require specific heterocyclic cores.
• Organic Electronic Materials: Serves as a building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Dye and Pigment Manufacturing: Acts as an intermediate for creating specialized dyes and pigments with specific color fastness and light-absorption properties.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Academic and Industrial R&D: A valuable reagent for method development and exploring new chemical spaces in synthetic chemistry laboratories.

Basic Information

Product Name	3-Amino-5-tert-Butyl-2-Nitro-Thiophene
CAS No.	1021443-95-7
Molecular Formula	C8H12N2O2S
Molecular Weight	200.26 g/mol
Synonyms	3-Amino-5-(tert-butyl)-2-nitrothiophene; 5-tert-Butyl-3-amino-2-nitrothiophene; 2-Nitro-5-tert-butylthiophen-3-amine; 3-Amino-5-tert-butyl-2-nitro-thiophene; 1021443-95-7; 3-Amino-5-(1,1-dimethylethyl)-2-nitrothiophene; 3-Amino-5-(tert-butyl)-2-nitro-thiophene
EINECS	Contact for details

Quality Control

Our 3-Amino-5-tert-Butyl-2-Nitro-Thiophene is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, purity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store this material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.