Description

Sulfathiazole-D4 CAS NO 1020719-89-4 is a deuterium-labeled analog of the classic sulfonamide antibiotic, Sulfathiazole, where four hydrogen atoms are replaced with deuterium. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring unparalleled accuracy and reliability in analytical measurements. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, biomedical research, and forensic toxicology sectors who require precise quantification of Sulfathiazole in complex matrices.

Application

• Internal Standard for LC-MS/MS and GC-MS: Primary application for the accurate quantification of Sulfathiazole in pharmacokinetic, metabolism, and bioanalytical studies.
• Pharmaceutical Research & Development: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the absorption, distribution, metabolism, and excretion of Sulfathiazole.
• Veterinary Drug Residue Analysis: Critical for ensuring food safety by detecting and quantifying Sulfathiazole residues in animal-derived products (meat, milk, honey) to comply with maximum residue limits (MRLs).
• Clinical and Forensic Toxicology: Enables precise measurement of Sulfathiazole levels in biological fluids for therapeutic drug monitoring or forensic investigations.
• Environmental Analysis: Employed in trace analysis of sulfonamide antibiotics in water and soil samples to study environmental persistence and impact.
• Method Development and Validation: Serves as a key component in developing and validating robust, regulatory-compliant analytical methods (e.g., following FDA, EMA guidelines).

Basic Information

Product Name	Sulfathiazole-D4
CAS No.	1020719-89-4
Molecular Formula	C9H5D4N3O2S2
Molecular Weight	259.34 g/mol
Synonyms	4-Amino-N-(2-thiazolyl)benzenesulfonamide-2,3,5,6-d4; Sulfathiazole (phenyl-d4); Sulfathiazole-d4; Deuterated Sulfathiazole; [2H4]-Sulfathiazole; 2-(p-Aminobenzenesulfonamido)thiazole-d4; N1-(2-Thiazolyl)sulfanilamide-d4; STZ-d4
EINECS	Contact for details

Quality Control

Every batch of Sulfathiazole-D4 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including HPLC for chemical purity, NMR and MS for isotopic enrichment verification, and identity confirmation. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Chemical Purity (by NMR)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.