Description

Ethyl 3-(Methyl-D3-Mercapto)Propionate is a deuterated isotopologue of a sulfur-containing ester, specifically featuring a methyl-d3 (CD3) group on the thiol moiety. This compound is primarily valued as a stable isotope-labeled building block and internal standard for advanced analytical and research applications, ensuring high precision in quantitative analysis. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors, particularly for metabolism studies, pharmacokinetics, and method development using mass spectrometry.

Application

• Pharmaceutical Research & Development: Serves as a stable isotope-labeled internal standard for the accurate quantification of metabolites and active pharmaceutical ingredients (APIs) in bioanalytical studies using LC-MS/MS.
• Metabolite Identification & Tracing: Used in drug metabolism and pharmacokinetics (DMPK) studies to trace metabolic pathways and improve the sensitivity of detection methods.
• Agrochemical Analysis: Employed as a reference standard in the environmental and residue analysis of sulfur-containing pesticides and their degradation products.
• Chemical Synthesis: Acts as a specialized deuterated synthon for the preparation of labeled analogs of more complex molecules in medicinal and organic chemistry.
• Forensic & Clinical Toxicology: Provides a reliable standard for the precise measurement of specific compounds in complex biological matrices.
• Quality Control & Method Validation: Critical for developing and validating robust analytical methods in GMP and GLP environments, ensuring regulatory compliance.

Basic Information

Product Name	Ethyl 3-(Methyl-D3-Mercapto)Propionate
CAS No.	1020719-41-8
Molecular Formula	C7H11D3O2S
Molecular Weight	163.25 g/mol
Synonyms	Ethyl 3-[(Methyl-d3)thio]propionate; Ethyl 3-(Methyl-d3-mercapto)propanoate; 3-[(Methyl-d3)sulfanyl]propanoic acid ethyl ester; Ethyl β-[(Methyl-d3)thio]propionate; Deuterated Ethyl 3-(Methylmercapto)propionate; (Methyl-d3)thiopropionic Acid Ethyl Ester; CD3SCH2CH2COOC2H5
EINECS	Contact for details

Quality Control

Our Ethyl 3-(Methyl-D3-Mercapto)Propionate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C) and mass spectrometry for isotopic enrichment and structural confirmation, as well as purity assessment by GC or HPLC. We provide Certificates of Analysis (COA) detailing isotopic purity, chemical purity, and specific impurities, supporting research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Isotopic Purity (D-content)	≥ 98 atom % D (by MS)
Chemical Purity (GC/HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.