Description

n-(Diphenylmethylidine)-3-(Aminomethyl)Pyridine-2,4,5,6-D4 is a deuterated pyridine derivative, specifically a deuterated analog of a Schiff base compound, which serves as a crucial building block in advanced chemical synthesis. This compound is valued for its role in the preparation of isotopically labeled molecules, which are essential for research in drug metabolism, pharmacokinetic studies, and analytical method development. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of analytical standards and reagents for mass spectrometry and NMR spectroscopy.

Application

• Pharmaceutical Research: As a key intermediate in the synthesis of deuterium-labeled active pharmaceutical ingredients (APIs) for use in drug discovery and development.
• Metabolic Studies: Used to create internal standards for Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) to accurately quantify drug metabolites.
• Mechanistic Investigations: Employed in reaction mechanism studies and kinetic isotope effect (KIE) experiments to elucidate biochemical pathways.
• Analytical Standard Manufacturing: Serves as a high-purity starting material for certified reference material (CRM) producers.
• Chemical Biology: Utilized in the development of molecular probes and labeled ligands for receptor binding assays.
• Material Science Research: Potential application in the synthesis of novel organic electronic materials where isotopic labeling can modify properties.

Basic Information

Product Name	n-(Diphenylmethylidine)-3-(Aminomethyl)Pyridine-2,4,5,6-D4
CAS No.	1020719-40-7
Molecular Formula	C19H15D4N2
Molecular Weight	279.39 g/mol
Synonyms	2,4,5,6-Tetradeutero-N-(diphenylmethylene)-3-(aminomethyl)pyridine; Deuterated Schiff Base Pyridine Derivative; 3-(Aminomethyl)-N-(diphenylmethylene)pyridine-2,4,5,6-d4; (Pyridine-2,4,5,6-d4)-3-(aminomethyl)-N-(diphenylmethylene)amine; N-(Diphenylmethylidene)-3-(aminomethyl)pyridine-2,4,5,6-d4; 3-(Aminomethyl)pyridine-2,4,5,6-d4, N-(diphenylmethylene) deriv.
EINECS	Contact for details

Quality Control

Our n-(Diphenylmethylidine)-3-(Aminomethyl)Pyridine-2,4,5,6-D4 is produced under strict quality management protocols to ensure the highest standards of isotopic and chemical purity required for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results from advanced analytical techniques including NMR (for deuterium incorporation), HPLC, and mass spectrometry. We are committed to supplying materials that meet the stringent requirements of GMP and ISO-guided environments for pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Incorporation (NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.