Description

2-Chloro-1-(Trideuteromethyl)-6-Phenylimidazo(4,5-B)Pyridine is a deuterated derivative of a key heterocyclic compound, offering enhanced metabolic stability and traceability for advanced research applications. This compound is valued for its role as a stable isotope-labeled internal standard or probe in analytical and pharmacological studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers specializing in drug metabolism and pharmacokinetics (DMPK) research.

Application

• As a stable isotope-labeled internal standard for the precise quantification of its non-deuterated counterpart in bioanalytical methods (LC-MS/MS).
• In drug metabolism and pharmacokinetics (DMPK) studies to investigate metabolic pathways and improve drug candidate profiles.
• For use in mechanistic pharmacology research as a molecular probe to study enzyme interactions and binding sites.
• As a critical intermediate or reference material in the development of deuterated drug candidates for improved therapeutic efficacy.
• In academic and industrial research focused on imidazopyridine chemistry and its biological activities.

Basic Information

Product Name	2-Chloro-1-(Trideuteromethyl)-6-Phenylimidazo(4,5-B)Pyridine
CAS No.	1020719-30-5
Molecular Formula	C₁₄H₁₀D₃ClN₃
Molecular Weight	261.75 g/mol
Synonyms	2-Chloro-1-(trideuteriomethyl)-6-phenyl-1H-imidazo[4,5-b]pyridine; 2-Chloro-1-(methyl-d3)-6-phenylimidazo[4,5-b]pyridine; 6-Phenyl-2-chloro-1-(trideuteromethyl)imidazo[4,5-b]pyridine; Deuterated 2-Chloro-1-methyl-6-phenylimidazo[4,5-b]pyridine; 1H-Imidazo[4,5-b]pyridine, 2-chloro-1-(trideuteriomethyl)-6-phenyl-; 1020719-30-5; (Trideuteromethyl)-6-phenylimidazo(4,5-B)Pyridine derivative
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control protocols to ensure high isotopic purity and chemical integrity. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, LC-MS, and HPLC. A comprehensive Certificate of Analysis (COA) is provided, detailing assay, isotopic enrichment (D-content), and impurity profiles. We support research compliance with traceable documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the material under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.