Description

5-Carboxy-n-Phenyl-2-1H-Pyridone-D5 is a deuterated isotopologue of a key heterocyclic carboxylic acid derivative, serving as a crucial stable isotope-labeled building block and internal standard. Its core value lies in enabling precise analytical quantification and metabolic pathway tracing in advanced research and development. This compound is essential for pharmaceutical, agrochemical, and academic laboratories engaged in deuterium labeling studies, mass spectrometry, and pharmacokinetic research.

Application

• Internal Standard for LC-MS/MS Analysis: Used as a quantitative reference standard in bioanalytical method development for drug and metabolite quantification.
• Metabolic Pathway Tracing: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of active pharmaceutical ingredients.
• Deuterated Pharmaceutical Intermediate: Acts as a labeled precursor in the synthesis of deuterium-labeled drug candidates for improved metabolic stability.
• Agrochemical Research: Utilized in environmental fate studies and residue analysis of pesticides and herbicides.
• NMR Spectroscopy: Serves as a probe in nuclear magnetic resonance studies due to the distinct signal of deuterium atoms.
• Isotope Dilution Mass Spectrometry (IDMS): A critical component in high-precision analytical techniques for accurate measurement of target analytes.

Basic Information

Product Name	5-Carboxy-n-Phenyl-2-1H-Pyridone-D5
CAS No.	1020719-24-7
Molecular Formula	C12H2D5NO3
Molecular Weight	~222.22 g/mol
Synonyms	5-Carboxy-2-phenylpyridin-1(2H)-one-d5; 1H-Pyridin-2-one, 5-carboxy-1-phenyl-, D5; 5-Carboxy-1-phenyl-2(1H)-pyridinone-d5; Deuterated 5-Carboxyphenyl-2-pyridone; 5-Carboxy-2-pyridone phenyl derivative-d5; [D5]-5-Carboxy-n-Phenyl-2-1H-Pyridone; Stable Isotope Labeled Pyridone Carboxylic Acid
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control to ensure high isotopic purity and chemical integrity, critical for analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and MS. Certificates of Analysis (COA) are provided, detailing isotopic enrichment (e.g., D5, >98 atom % D), chemical purity, and analytical results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D (D5)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.