Description

2-Butyne-1,4-Diol-(1,1,4,4)-D4, Diacetate is a deuterium-labeled derivative of 2-Butyne-1,4-diol diacetate, serving as a crucial internal standard and tracer in advanced analytical chemistry. This high-purity compound is essential for ensuring accuracy and reliability in quantitative mass spectrometry and metabolic studies. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories engaged in pharmacokinetics, drug metabolism research, and stable isotope labeling.

Application

• Internal Standard for Mass Spectrometry (MS): Provides precise quantification in LC-MS and GC-MS analyses due to its isotopic purity, minimizing matrix effects.
• Metabolic Pathway Tracing: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of molecules in biological systems.
• Pharmaceutical Research & Development: Critical for the development and validation of bioanalytical methods for new chemical entities.
• Stable Isotope Labeling: Acts as a labeled precursor or intermediate in the synthesis of more complex deuterated compounds for research.
• Analytical Reference Standard: Ensures method accuracy and compliance in quality control laboratories for regulatory submissions.
• Chemical Mechanism Studies: Utilized in mechanistic studies to elucidate reaction pathways using isotope effects.

Basic Information

Product Name	2-Butyne-1,4-Diol-(1,1,4,4)-D4, Diacetate
CAS No.	1020719-23-6
Molecular Formula	C8H6D4O4
Molecular Weight	174.19 g/mol (approx.)
Synonyms	2-Butyne-1,4-diol-1,1,4,4-d4 Diacetate; 1,4-Diacetoxy-2-butyne-1,1,4,4-d4; 2-Butyne-1,4-diol Diacetate-d4; But-2-yne-1,4-diyldiacetate-d4; Deuterated 2-Butyne-1,4-diol Diacetate; [1,1,4,4-2H4]-2-Butyne-1,4-diol Diacetate; Tetradeuterated 2-Butyne-1,4-diol Diacetate; 1,4-Bis(acetoxy)-2-butyne-d4
EINECS	Contact for details

Quality Control

Every batch of our deuterated compounds is produced and analyzed under strict quality control protocols to ensure exceptional isotopic and chemical purity suitable for sensitive analytical applications. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (D-atom %), chemical purity by HPLC/GC, and identity confirmation by NMR and MS. Our quality system is designed to meet the rigorous standards required for research and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0% (on labeled positions)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.