Description

2-sec-Butyl-D5-4-{4-[4-(4-Methyloxy-Phenyl)-Piperazin-1-Yl]-Phenyl}-2,4-Dihydro-[1,2,4]-Triazol-3-One is a high-purity, deuterated organic compound of significant interest in advanced pharmaceutical research and development. Its core value lies in its utility as a stable isotope-labeled internal standard or a key synthetic intermediate for pharmacokinetic and metabolic studies. This compound is primarily needed by research institutions, analytical laboratories, and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within the fields of neuroscience and receptor-targeted drug discovery.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quantitative analysis in drug development pipelines.
• Metabolite Tracing & Pharmacokinetics: Used as a deuterium-labeled internal standard in LC-MS/MS and GC-MS assays to accurately quantify drug and metabolite levels in biological matrices.
• Medicinal Chemistry Research: Acts as a crucial building block or intermediate in the synthesis of novel triazolone and piperazine-based bioactive molecules.
• Biochemical Assay Development: Employed in receptor binding studies and enzyme inhibition assays to investigate mechanism of action.
• Isotope-Labeled Probe Synthesis: Utilized for creating molecular probes for advanced imaging and diagnostic research applications.

Basic Information

Product Name	2-sec-Butyl-D5-4-{4-[4-(4-Methyloxy-Phenyl)-Piperazin-1-Yl]-Phenyl}-2,4-Dihydro-[1,2,4]-Triazol-3-One
CAS No.	1020719-22-5
Molecular Formula	C23H24D5N5O2
Molecular Weight	~406.56 g/mol
Synonyms	2-(sec-Butyl-d5)-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-1,2,4-triazol-3-one; 2-(1-Methylpropyl-d5)-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one; Deuterated Triazolone Piperazine Derivative; 1020719-22-5; CAS 1020719-22-5
EINECS	Contact for details

Quality Control

Our 2-sec-Butyl-D5-4-{4-[4-(4-Methyloxy-Phenyl)-Piperazin-1-Yl]-Phenyl}-2,4-Dihydro-[1,2,4]-Triazol-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and isotopic enrichment suitable for research applications. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.