Description

2-sec-Butyl-D5-4-(4-[4-(4-Hydroxy-Phenyl)-Piperazin-1-Yl]-Phenyl)-2,4-Dihydro-[1,2,4]-Triazol-3-One is a high-purity, deuterated organic compound of significant interest in advanced pharmaceutical research and development. Its core value lies in its role as a stable isotope-labeled analog, which is essential for precise pharmacokinetic, metabolic, and bioanalytical studies. This product is primarily needed by research institutions, pharmaceutical companies, and contract research organizations (CROs) engaged in the development of novel therapeutic agents, particularly for creating internal standards in mass spectrometry.

Application

• Pharmaceutical Reference Standard: Serves as a critical certified reference material (CRM) for quantitative analysis in drug development.
• Metabolic Studies: Used as a stable isotope-labeled internal standard in LC-MS/MS and GC-MS to accurately trace drug metabolism and absorption.
• Bioanalytical Research: Essential for method development and validation in pharmacokinetic (PK) and pharmacodynamic (PD) studies to ensure data reliability.
• Drug Discovery & Development: Acts as a key intermediate or analytical tool in the synthesis and testing of new chemical entities targeting central nervous system or endocrine pathways.
• Isotope Dilution Mass Spectrometry (IDMS): Employed for achieving high-precision and high-accuracy measurements in complex biological matrices.
• Regulatory Submissions: Supports investigational new drug (IND) and new drug application (NDA) filings by providing validated analytical data.

Basic Information

Product Name	2-sec-Butyl-D5-4-(4-[4-(4-Hydroxy-Phenyl)-Piperazin-1-Yl]-Phenyl)-2,4-Dihydro-[1,2,4]-Triazol-3-One
CAS No.	1020719-21-4
Molecular Formula	C22H22D5N5O2
Molecular Weight	Contact for details
Synonyms	2-(sec-Butyl-d5)-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-1,2,4-triazol-3-one; 2-(1-Methylpropyl-d5)-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one; Deuterated Triazolone Derivative; 2-sec-Butyl-D5-4-(4-(4-(4-Hydroxyphenyl)piperazin-1-yl)phenyl)-4H-1,2,4-triazol-3-one; [1,2,4]Triazol-3-one, 2-(1-methylpropyl-d5)-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2,4-dihydro-; CAS 1020719-21-4
EINECS	Contact for details

Quality Control

Our 2-sec-Butyl-D5-4-(4-[4-(4-Hydroxy-Phenyl)-Piperazin-1-Yl]-Phenyl)-2,4-Dihydro-[1,2,4]-Triazol-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and isotopic enrichment meet exacting standards. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.