Description

(R,S)-Anabasine-2,4,5,6-D4 is a deuterium-labeled analog of the alkaloid anabasine, serving as a critical internal standard for precise analytical quantification. This high-purity, isotopically labeled compound is essential for ensuring accuracy and reliability in sensitive mass spectrometry and chromatography-based methods. It is primarily required by analytical laboratories, pharmaceutical researchers, and agrochemical developers engaged in metabolism studies, pharmacokinetic research, and environmental residue analysis.

Application

• Internal Standard for LC-MS/MS and GC-MS: Used for the accurate quantification of anabasine and related alkaloids in complex biological and environmental matrices.
• Metabolite Tracing and Pharmacokinetic Studies: Enables detailed investigation of drug metabolism, absorption, distribution, and excretion (ADME) profiles.
• Forensic and Clinical Toxicology: Supports the development and validation of highly specific assays for detecting nicotine-like alkaloids.
• Agrochemical Research: Facilitates the study of plant alkaloid pathways and the analysis of pesticide or herbicide residues.
• Neuroscience and Receptor Binding Studies: Acts as a tool compound for research on nicotinic acetylcholine receptors (nAChRs).
• Quality Control and Method Development: Critical for validating analytical methods in compliance with GLP and GMP guidelines.

Basic Information

Product Name	(R,S)-Anabasine-2,4,5,6-D4
CAS No.	1020719-08-7
Molecular Formula	C10H10D4N2
Molecular Weight	164.25 g/mol
Synonyms	Anabasine-d4; DL-Anabasine-2,4,5,6-d4; 3-(Piperidin-2-yl)pyridine-2,4,5,6-d4; 2-(3-Pyridyl)piperidine-2,4,5,6-d4; Neonicotine-d4; (Rac)-Anabasine-d4; (RS)-Anabasine-2,4,5,6-D4
EINECS	Contact for details

Quality Control

Every batch of (R,S)-Anabasine-2,4,5,6-D4 is manufactured and tested under strict quality management systems to ensure the highest standards of isotopic purity and chemical integrity. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic analyses, to ensure compliance with research and analytical standards. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.