Description

Anabaseine-D4 CAS NO 1020719-05-4 is a deuterated analog of the natural alkaloid anabaseine, specifically labeled with four deuterium atoms. This stable isotope-labeled compound is essential for advanced analytical research, providing a critical internal standard for precise quantification and metabolic pathway tracing. It is primarily utilized by researchers and developers in the pharmaceutical, agrochemical, and life science industries for applications in mass spectrometry, pharmacokinetic studies, and biochemical research.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical reference compound in LC-MS and GC-MS analyses for the accurate quantification of anabaseine and related metabolites.
• Pharmacokinetic and Metabolic Studies: Used in drug discovery and development to trace absorption, distribution, metabolism, and excretion (ADME) pathways.
• Biochemical Research: Acts as a tool for studying nicotinic acetylcholine receptor (nAChR) interactions and neuropharmacological mechanisms.
• Deuterium-Labeled Synthesis Intermediate: Employed in the synthesis of more complex deuterated molecules for research and development.
• Quality Control and Method Development: Supports the development and validation of robust analytical methods in regulatory and quality assurance laboratories.

Basic Information

Product Name	Anabaseine-D4
CAS No.	1020719-05-4
Molecular Formula	C10H10D4N2
Molecular Weight	162.24 g/mol (for deuterated form)
Synonyms	3-(2,3,4,5-Tetradeutero-1H-pyrrol-2-yl)pyridine; 2-(3-Pyridyl)-3,4,5,6-tetradeutero-1H-pyrrole; Deuterated Anabaseine; Anabaseine-d4; (3,4,5,6-2H4)-Anabaseine; 2-(Pyridin-3-yl)-1H-pyrrole-3,4,5,6-d4; Stable Isotope Labeled Anabaseine
EINECS	Contact for details

Quality Control

Our Anabaseine-D4 is produced under strict quality management protocols to ensure the highest isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and Mass Spectrometry to confirm isotopic enrichment and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (e.g., D% > 98%), chemical purity (by HPLC), and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under an inert atmosphere at -20°C to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D%)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.