Description

3-(Aminomethyl)Pyridine-2,4,5,6-D4 is a deuterated analog of 3-(aminomethyl)pyridine, where four hydrogen atoms are replaced with deuterium, a stable isotope of hydrogen. This deuteration is crucial for modifying the metabolic profile and physicochemical properties of molecules, making it a valuable tool in advanced research and development. This compound is primarily utilized by pharmaceutical and agrochemical researchers, as well as analytical laboratories, for applications in drug discovery, metabolic studies, and as an internal standard in mass spectrometry.

Application

• Pharmaceutical Research & Drug Discovery: Used as a deuterated building block to create isotopically labeled drug candidates for pharmacokinetic (PK), pharmacodynamic (PD), and absorption, distribution, metabolism, and excretion (ADME) studies.
• Metabolic Pathway Tracing: Serves as a stable isotope tracer to investigate biochemical pathways and metabolic stability in vivo, leveraging the kinetic isotope effect (KIE).
• Analytical Chemistry Standard: Employed as a high-purity internal standard for quantitative analysis via Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS), improving accuracy.
• Agrochemical Development: Incorporated into the synthesis of novel, labeled agrochemicals to study environmental fate, degradation, and residue analysis.
• Material Science Research: Explored in the development of advanced organic materials and ligands for catalysis where isotopic labeling is beneficial.
• Chemical Biology Probes: Utilized in the synthesis of isotopically labeled probes for mechanistic studies and protein-ligand interaction analysis.

Basic Information

Product Name	3-(Aminomethyl)Pyridine-2,4,5,6-D4
CAS No.	1020719-00-9
Molecular Formula	C6D4H4N2
Molecular Weight	112.16 g/mol
Synonyms	3-(Aminomethyl)pyridine-d4; 2,4,5,6-Tetradeutero-3-(aminomethyl)pyridine; 3-Picolylamine-2,4,5,6-d4; (Pyridine-2,4,5,6-d4-3-yl)methanamine; 3-(Aminomethyl)pyridine (2,4,5,6-D4); Deuteronated 3-Picolylamine; 3-Pyridinemethanamine-2,4,5,6-d4
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced and controlled under a strict quality management system. Each batch of 3-(Aminomethyl)Pyridine-2,4,5,6-D4 undergoes rigorous analytical testing, including NMR (Nuclear Magnetic Resonance) and MS (Mass Spectrometry), to confirm isotopic purity (typically >98 atom % D) and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC or HPLC)	≥ 95%
Isotopic Purity (Atom % D)	≥ 98%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.