Description

4-n-Acetylaminobenzene-D5-Sulfonyl Chloride is a deuterated derivative of a key sulfonyl chloride intermediate, specifically labeled with five deuterium atoms. This deuteration is critical for applications requiring high sensitivity and specificity, such as in mass spectrometry and metabolic studies, where it serves as an internal standard to enhance analytical accuracy. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for the development and analysis of novel compounds.

Application

• As a deuterated internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for quantitative bioanalysis.
• As a key labeled synthetic intermediate in the research and development of novel pharmaceutical compounds, including potential active pharmaceutical ingredients (APIs).
• In the synthesis of deuterated dyes, pigments, and advanced organic materials for research in photonics and electronics.
• For metabolic pathway tracing and pharmacokinetic studies in preclinical and clinical research.
• In the development of agrochemicals, where deuterium labeling is used to study environmental fate and metabolic degradation.
• As a specialized reagent in organic synthesis laboratories for introducing the sulfonyl chloride functional group in a deuterated context.

Basic Information

Product Name	4-n-Acetylaminobenzene-D5-Sulfonyl Chloride
CAS No.	1020718-84-6
Molecular Formula	C8H3D5ClNO3S
Molecular Weight	~244.72 g/mol
Synonyms	4-Acetamidobenzenesulfonyl Chloride-d5; N-Acetyl-4-aminobenzenesulfonyl Chloride-d5; p-Acetamidobenzenesulfonyl Chloride-d5; 4-(Acetylamino)benzenesulfonyl Chloride-d5; Deuterated Sulfacetamide Chloride; ABS-Cl-d5; Sulfonyl Chloride-d5 Intermediate; [D5]-4-Acetamidobenzenesulfonyl Chloride
EINECS	Contact for details

Quality Control

Every batch of 4-n-Acetylaminobenzene-D5-Sulfonyl Chloride is produced and tested under stringent quality management protocols to ensure exceptional isotopic purity and chemical integrity. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D5), chemical purity, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D5, NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.