Description

Ethyl 6-Bromoisoquinoline-1-Carboxylate is a high-purity brominated isoquinoline derivative serving as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products.
• Material Science: Building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology: Useful as a probe or tag in medicinal chemistry programs due to the reactive bromine handle for further functionalization.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and discovery chemistry.
• Custom Synthesis: Serves as a starting material for the contract manufacturing of bespoke fine chemicals and advanced intermediates.

Basic Information

Product Name	Ethyl 6-Bromoisoquinoline-1-Carboxylate
CAS No.	1020576-70-8
Molecular Formula	C₁₂H₁₀BrNO₂
Molecular Weight	280.12 g/mol
Synonyms	6-Bromo-1-isoquinolinecarboxylic acid ethyl ester; Ethyl 6-bromo-1-isoquinolinecarboxylate; 1-Carbethoxy-6-bromoisoquinoline; 6-Bromoisoquinoline-1-carboxylic acid ethyl ester; 1020576-70-8; Ethyl 6-bromoisoquinoline-1-carboxylate; Ethyl 6-bromo-1-isoquinolinecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromoisoquinoline-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere if opened frequently to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.