Description

6-(Piperidin-4-Yl)Isoquinoline Dihydrochloride is a high-purity organic salt of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and pharmacological probe in medicinal chemistry programs. It is primarily utilized by research institutions and pharmaceutical companies focused on discovering and optimizing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Tool Compound: Employed in in vitro and in vivo studies to investigate specific biological pathways and protein interactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	6-(Piperidin-4-Yl)Isoquinoline Dihydrochloride
CAS No.	1020277-43-3
Molecular Formula	C₁₄H₁₈N₂·2HCl
Molecular Weight	295.22 g/mol (free base: 214.31 g/mol)
Synonyms	6-(4-Piperidinyl)isoquinoline dihydrochloride; 6-(Piperidin-4-yl)isoquinoline hydrochloride (1:2); 6-(1,2,3,6-Tetrahydropyridin-4-yl)isoquinoline dihydrochloride (tautomer); 6-(1,2,3,6-Tetrahydro-4-pyridinyl)isoquinoline dihydrochloride; 4-(Isoquinolin-6-yl)piperidine dihydrochloride; 1020277-43-3; UNII-7Q9R4W3P1F
EINECS	Contact for details

Quality Control

Our 6-(Piperidin-4-Yl)Isoquinoline Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.