Description

2-[3,4-Dihydro-2(1H)-Isoquinolinyl]-Isonicotinic Acid is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound serves as a critical building block for the synthesis of novel bioactive molecules, particularly in the development of central nervous system (CNS) and receptor-targeting therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Ligand Development: Employed in the creation of novel ligands for receptor binding assays and pharmacological profiling.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex heterocyclic compounds in custom synthesis projects.
• Biochemical Tool Compound: Potential use in developing probes for studying biological pathways and enzyme interactions.

Basic Information

Product Name	2-[3,4-Dihydro-2(1H)-Isoquinolinyl]-Isonicotinic Acid
CAS No.	1019375-24-6
Molecular Formula	C15H14N2O2
Molecular Weight	254.28 g/mol
Synonyms	2-(3,4-Dihydro-1H-isoquinolin-2-yl)isonicotinic acid; 2-(3,4-Dihydroisoquinolin-2(1H)-yl)isonicotinic acid; 2-(1,2,3,4-Tetrahydroisoquinolin-2-yl)pyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 2-(1,2,3,4-tetrahydro-2-isoquinolinyl)-; 1019375-24-6; 2-(3,4-Dihydro-2H-isoquinolin-2-yl)isonicotinic acid
EINECS	Contact for details

Quality Control

Our production of 2-[3,4-Dihydro-2(1H)-Isoquinolinyl]-Isonicotinic Acid adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.