Description

5-[2-(2,3-Dihydro-1H-Indol-1-Yl)Ethyl]-1,3,4-Thiadiazol-2-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold that combines indoline and 1,3,4-thiadiazole pharmacophores. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in the areas of central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates for clinical research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Employed in vitro and in vivo to study specific biological pathways and validate new therapeutic targets.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for the cGMP production of active pharmaceutical ingredients (APIs) under development.

Basic Information

Product Name	5-[2-(2,3-Dihydro-1H-Indol-1-Yl)Ethyl]-1,3,4-Thiadiazol-2-Amine
CAS No.	1019111-89-7
Molecular Formula	C12H14N4S
Molecular Weight	246.33 g/mol
Synonyms	1,3,4-Thiadiazol-2-amine, 5-[2-(2,3-dihydro-1H-indol-1-yl)ethyl]-; 5-(2-Indolin-1-ylethyl)-1,3,4-thiadiazol-2-amine; 2-Amino-5-[2-(2,3-dihydro-1H-indol-1-yl)ethyl]-1,3,4-thiadiazole; 1019111-89-7; 5-(2-(2,3-Dihydro-1H-indol-1-yl)ethyl)-1,3,4-thiadiazol-2-amine
EINECS	Contact for details

Quality Control

Our 5-[2-(2,3-Dihydro-1H-Indol-1-Yl)Ethyl]-1,3,4-Thiadiazol-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available for every shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.