Description

3-Acetylsulfanyl-1-Boc-Piperidine is a high-purity, protected piperidine derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the acetylsulfanyl functional group under mild conditions, enabling the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Peptidomimetic Chemistry: Used to incorporate modified piperidine scaffolds into peptide backbones to enhance stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for ligands in asymmetric catalysis or as a functional handle in material science.
• Agrochemical Synthesis: Employed in the creation of novel herbicides, fungicides, and insecticides requiring specific sulfur-containing heterocycles.
• Chemical Biology Probes: Useful for labeling or modifying biomolecules to study protein function and interaction pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for scale-up and production under cGMP guidelines for clinical trial material.

Basic Information

Product Name	3-Acetylsulfanyl-1-Boc-Piperidine
CAS No.	1017798-33-2
Molecular Formula	C12H21NO3S
Molecular Weight	259.36 g/mol
Synonyms	1-Boc-3-(Acetylthio)piperidine; tert-Butyl 3-(Acetylsulfanyl)piperidine-1-carboxylate; 3-(Acetylthio)-1-(tert-butoxycarbonyl)piperidine; 1-(tert-Butoxycarbonyl)-3-(acetylthio)piperidine; 3-Acetylthio-1-Boc-piperidine; N-Boc-3-mercaptopiperidine acetate; Piperidine, 3-(acetylthio)-1-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Every batch of 3-Acetylsulfanyl-1-Boc-Piperidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is supplied with each shipment. Specifications can be aligned with research-grade or cGMP requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be kept under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.