Description

2-Ethoxy-3,5-Difluorobenzyl Bromide is a high-purity, multi-functional organic building block essential for advanced chemical synthesis. This compound is valued for its reactive benzyl bromide moiety and strategically placed fluorine and ethoxy substituents, which enable precise molecular modifications. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex, bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the difluoro and ethoxy groups contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and liquid crystals, where its aromatic core and halogen functionality allow for controlled polymerization and mesogen formation.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP conditions for clinical trial material production.

Basic Information

Product Name	2-Ethoxy-3,5-Difluorobenzyl Bromide
CAS No.	1017779-82-6
Molecular Formula	C9H9BrF2O
Molecular Weight	251.07 g/mol
Synonyms	1-(Bromomethyl)-2-ethoxy-3,5-difluorobenzene; 3,5-Difluoro-2-ethoxybenzyl Bromide; (2-Ethoxy-3,5-difluorophenyl)methyl Bromide; 2-Ethoxy-3,5-difluoro-α-bromotoluene; Benzene, 1-(bromomethyl)-2-ethoxy-3,5-difluoro-; 2-Ethoxy-3,5-difluorobenzylbromide; α-Bromo-2-ethoxy-3,5-difluorotoluene
EINECS	Contact for details

Quality Control

Every batch of 2-Ethoxy-3,5-Difluorobenzyl Bromide is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.