Description

2-(3,4-Dihydroisoquinolin-2(1H)-Yl)-4-Methylpyrimidine-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and central nervous system (CNS) disorders. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs) and other biologically active molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• API Synthesis: Serves as a crucial precursor in the multi-step synthesis of complex active pharmaceutical ingredients.
• Biochemical Research: Employed as a tool compound or ligand in biochemical assays and target validation studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional laboratories for exploratory synthetic and pharmacological research.

Basic Information

Product Name	2-(3,4-Dihydroisoquinolin-2(1H)-Yl)-4-Methylpyrimidine-5-Carboxylic Acid
CAS No.	1017485-42-5
Molecular Formula	C15H15N3O2
Molecular Weight	269.30 g/mol
Synonyms	4-Methyl-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine-5-carboxylic acid; 2-(1,2,3,4-Tetrahydroisoquinolin-2-yl)-4-methylpyrimidine-5-carboxylic acid; 2-(3,4-Dihydro-1H-isoquinolin-2-yl)-4-methylpyrimidine-5-carboxylic acid; 1017485-42-5; UNII-9J3S5I6Q4K; 9J3S5I6Q4K; SCHEMBL2180625; DTXSID90664669
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dihydroisoquinolin-2(1H)-Yl)-4-Methylpyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.