Description

1-(2'-Fluoro)Phenyl-1,2,3,4-Tetrahydro-Isoquinoline is a high-purity fluorinated isoquinoline derivative, a key advanced intermediate in modern organic synthesis. Its value lies in its unique molecular scaffold, which is crucial for constructing complex pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs due to its fluorinated aromatic system.
• Agrochemical Development: Acts as a precursor in the creation of new pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Material Science Precursor: Employed in the synthesis of specialized ligands for catalysis or functional organic materials.
• Academic & Contract Research: Utilized in universities and CROs (Contract Research Organizations) for methodological development and exploratory synthesis.

Basic Information

Product Name	1-(2'-Fluoro)Phenyl-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	1017125-85-7
Molecular Formula	C15H14FN
Molecular Weight	227.28 g/mol
Synonyms	1-(2-Fluorophenyl)-1,2,3,4-tetrahydroisoquinoline; 1-(2-Fluorophenyl)-3,4-dihydro-1H-isoquinoline; 2-Fluoro-1-(1,2,3,4-tetrahydroisoquinolin-1-yl)benzene; 1-(2-Fluorophenyl)-1,2,3,4-tetrahydro-isoquinoline; 1017125-85-7; FPTIQ
EINECS	Contact for details

Quality Control

Our production of 1-(2'-Fluoro)Phenyl-1,2,3,4-Tetrahydro-Isoquinoline adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.