Description

1-[2-(2,3-Dihydro-1H-Indol-3-Yl)Ethyl]Pyrrolidin-2-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in innovative drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug candidates, especially in neurological and psychiatric therapeutic areas.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Contract Manufacturing: Supplied to CDMOs for the cGMP production of clinical trial materials and commercial APIs.
• Biochemical Research: Employed as a research tool to study biological pathways and receptor interactions due to its specific molecular scaffold.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	1-[2-(2,3-Dihydro-1H-Indol-3-Yl)Ethyl]Pyrrolidin-2-One
CAS No.	1016794-28-7
Molecular Formula	C14H18N2O
Molecular Weight	230.31 g/mol
Synonyms	1-[2-(2,3-Dihydro-1H-indol-3-yl)ethyl]pyrrolidin-2-one; 1-[2-(Indolin-3-yl)ethyl]-2-pyrrolidinone; 2-Pyrrolidinone, 1-[2-(2,3-dihydro-1H-indol-3-yl)ethyl]-; 3-[2-(2-Oxo-1-pyrrolidinyl)ethyl]-1H-indole; 1-(2-Indolin-3-ylethyl)pyrrolidin-2-one; 1016794-28-7; UNII-7F6Q3F2W3N
EINECS	Contact for details

Quality Control

Our 1-[2-(2,3-Dihydro-1H-Indol-3-Yl)Ethyl]Pyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with ICH guidelines, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.