Description

2-Oxo-2,3-Dihydrobenzo[D]Oxazol-6-Yl-Boronic Acid is a high-value, heterocyclic boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process R&D teams developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional organic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those containing benzoxazole or related heterocyclic scaffolds.
• Suzuki-Miyaura Cross-Coupling: A versatile boronic acid reagent for palladium-catalyzed coupling reactions to create biaryl and other conjugated structures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Building block for organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is required.
• Chemical Biology & Proteomics: Potential use in the development of enzyme inhibitors or as a handle for bioconjugation and probe synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-directed research and scale-up projects.

Basic Information

Product Name	2-Oxo-2,3-Dihydrobenzo[D]Oxazol-6-Yl-Boronic Acid
CAS No.	1016644-38-4
Molecular Formula	C8H6BNO4
Molecular Weight	190.95 g/mol
Synonyms	6-Borono-2,3-dihydro-2-oxobenzoxazole; 2,3-Dihydro-2-oxobenzoxazol-6-ylboronic Acid; 2-Oxo-2,3-dihydro-1,3-benzoxazol-6-ylboronic Acid; 2-Oxobenzo[d]oxazol-6-ylboronic Acid; Benzo[d]oxazol-6-ylboronic Acid, 2,3-dihydro-2-oxo-; 1016644-38-4; (2-Oxo-2,3-dihydrobenzo[d]oxazol-6-yl)boronic Acid
EINECS	Contact for details

Quality Control

Our 2-Oxo-2,3-Dihydrobenzo[D]Oxazol-6-Yl-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and ICP-MS for heavy metal screening, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent performance in your critical coupling reactions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals (ICP-MS)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.