Description

2-[(3-Fluorophenyl)Methyl]Pyrrolidine is a fluorinated pyrrolidine derivative, a versatile and valuable building block in modern organic synthesis. Its structure, featuring a fluorinated aromatic ring linked to a pyrrolidine moiety, makes it a critical intermediate for developing novel compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the synthesis of advanced pesticides and herbicides, where the fluorine atom can improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with specific electronic or structural properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-[(3-Fluorophenyl)Methyl]Pyrrolidine
CAS No.	1016499-34-5
Molecular Formula	C11H14FN
Molecular Weight	179.24 g/mol
Synonyms	1-(3-Fluorobenzyl)pyrrolidine; 2-[(3-Fluorophenyl)methyl]pyrrolidine; 3-Fluorobenzylpyrrolidine; N-(3-Fluorobenzyl)pyrrolidine; 1-[(3-Fluorophenyl)methyl]pyrrolidine; Pyrrolidine, 2-[(3-fluorophenyl)methyl]-; (3-Fluorobenzyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 2-[(3-Fluorophenyl)Methyl]Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.