Description

6-Fluoro-1,4-Dihydro-4-Oxo-1-Pentadeuteroethyl-7-Piperazino-3-Quinolinecarboxylic Acid is a deuterated derivative of a key fluoroquinolone carboxylic acid intermediate, offering a stable isotopic label for advanced research and development. This compound is critical for applications requiring precise metabolic tracking and enhanced analytical sensitivity in pharmacokinetic studies. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers specializing in the synthesis of novel antibacterial agents and diagnostic tracers.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of deuterium-labeled fluoroquinolone antibiotics, enabling drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolic Tracer: Used in mass spectrometry and NMR-based research to track the metabolic pathways and bioavailability of active pharmaceutical ingredients (APIs).
• Reference Standard: Serves as a high-purity certified reference material (CRM) for analytical method development and validation in quality control laboratories.
• Isotope-Labeled Probe Development: Essential for creating molecular probes in biomedical research to investigate drug-receptor interactions and mechanisms of action.
• Process Chemistry: Employed in the development and scaling of synthetic routes for next-generation antibacterial agents under GMP conditions.

Basic Information

Product Name	6-Fluoro-1,4-Dihydro-4-Oxo-1-Pentadeuteroethyl-7-Piperazino-3-Quinolinecarboxylic Acid
CAS No.	1015856-57-1
Molecular Formula	C₁₆H₁₃D₅FN₃O₃
Molecular Weight	330.35 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-7-piperazin-1-yl-4-oxo-quinoline-3-carboxylic Acid-d5; 1-Cyclopropyl-d5-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid; 6-Fluoro-1,4-dihydro-4-oxo-1-(cyclopropyl-d5)-7-(1-piperazinyl)-3-quinolinecarboxylic Acid; Deuterated Ciprofloxacin Acid Intermediate; 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic-1-d5 Acid; [1,2,2,3,3-d5]-1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 6-Fluoro-1,4-Dihydro-4-Oxo-1-Pentadeuteroethyl-7-Piperazino-3-Quinolinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and isotopic enrichment, NMR for structural confirmation, and MS for molecular weight verification, to ensure compliance with research-grade and GMP intermediate standards. Comprehensive Certificates of Analysis (COA) with detailed chromatographic data are provided.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content, MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.