Description

8-Bromo-5H-Pyrido[4,3-B]Indole is a high-purity heterocyclic organic compound, specifically a brominated pyridoindole derivative, serving as a critical building block in advanced chemical synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex pharmacophores and functional materials. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used as a precursor in the synthesis of new-generation herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for organic semiconductors, light-emitting diodes (OLEDs), and other functional organic materials due to its fused-ring, electron-rich structure.
• Chemical Biology: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Academic & Contract Research: Essential for methodological development in organic synthesis and for creating bespoke compound libraries for high-throughput screening.

Basic Information

Product Name	8-Bromo-5H-Pyrido[4,3-B]Indole
CAS No.	1015460-56-6
Molecular Formula	C11H7BrN2
Molecular Weight	247.09 g/mol
Synonyms	8-Bromo-5H-pyrido[4,3-b]indole; 8-Bromopyrido[4,3-b]indole; 5H-Pyrido[4,3-b]indole, 8-bromo-; 8-Bromo-5H-β-carboline; 8-Bromobeta-carboline; 8-Bromo-β-carboline; 8-Bromo-9H-pyrido[3,4-b]indole (tautomeric form)
EINECS	Contact for details

Quality Control

Our 8-Bromo-5H-Pyrido[4,3-B]Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive compound from degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.