Description

6-Ethynylisoquinoline is a high-value, functionalized isoquinoline derivative characterized by its terminal alkyne moiety, making it a versatile building block in advanced organic synthesis. This compound matters for its critical role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, enabling click chemistry and cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its structural motif for bioactivity.
• Material Science: Acts as a monomer or cross-linking agent in the production of advanced polymers, metal-organic frameworks (MOFs), and conductive materials.
• Chemical Biology & Proteomics: Employed in bioconjugation and labeling strategies via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Ligand Synthesis: Utilized for preparing novel nitrogen-containing ligands for catalysis and metal complexation.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	6-Ethynylisoquinoline
CAS No.	1015070-57-1
Molecular Formula	C11H7N
Molecular Weight	153.18 g/mol
Synonyms	6-Ethynylisoquinoline; Isoquinoline, 6-ethynyl-; 6-Ethynyl-isoquinoline; 6-Ethynyl-2-azanaphthalene; 6-Ethynyl-1-azanaphthalene; 1015070-57-1
EINECS	Contact for details

Quality Control

Our 6-Ethynylisoquinoline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep the container tightly sealed in a dry, cool, and well-ventilated place. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.