Description

1-Benzyl-4-Piperidinol-2,2,6,6-D4 is a deuterium-labeled analog of 1-benzyl-4-piperidinol, a key intermediate in organic synthesis. This compound matters for its utility in advanced research and development, particularly in mechanistic studies and as an internal standard in analytical chemistry. It is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and analytical laboratories focused on metabolism, pharmacokinetics, and stable isotope labeling.

Application

• Pharmaceutical Research: Used as a deuterated building block in the synthesis of isotopically labeled drug candidates for metabolism and pharmacokinetic (DMPK) studies.
• Analytical Chemistry: Serves as a high-purity internal standard for the accurate quantification of its non-deuterated counterpart in complex matrices using LC-MS or GC-MS.
• Mechanistic Studies: Employed in reaction mechanism elucidation and isotope effect investigations due to the kinetic isotope effect (KIE) of the deuterium atoms.
• Agrochemical Development: Utilized in the synthesis of labeled pesticide or herbicide analogs for environmental fate and residue analysis studies.
• Material Science: Acts as a precursor for specialized polymers or ligands where isotopic labeling is required for spectroscopic analysis.

Basic Information

Product Name	1-Benzyl-4-Piperidinol-2,2,6,6-D4
CAS No.	1014695-50-1
Molecular Formula	C12H13D4NO
Molecular Weight	191.28 g/mol
Synonyms	4-Piperidinol, 1-(phenylmethyl)-, 2,2,6,6-d4-; 1-Benzyl-4-hydroxypiperidine-2,2,6,6-d4; N-Benzyl-4-piperidinol-d4; 1-Benzylpiperidin-4-ol-2,2,6,6-d4; 4-Hydroxy-1-benzylpiperidine-2,2,6,6-d4; N-Benzyl-4-hydroxy-piperidine-d4; [2,2,6,6-2H4]-1-Benzyl-4-piperidinol
EINECS	Contact for details

Quality Control

Our 1-Benzyl-4-Piperidinol-2,2,6,6-D4 is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and MS, to ensure high chemical purity and isotopic enrichment. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and deuterium content is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider sealing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.