Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-2-(1,1-Dimethylethyl)- is a high-value brominated heterocyclic building block, specifically a substituted pyrrolopyridine derivative. This compound is critical for medicinal chemistry research and development, serving as a versatile scaffold for constructing novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and CNS drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Kinase Inhibitor Development: The pyrrolopyridine core is a privileged structure in the design of protein kinase inhibitors for cancer therapy.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection products.
• Material Science: Can be employed in the synthesis of organic electronic materials and ligands for catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-2-(1,1-Dimethylethyl)-
CAS No.	1014613-61-6
Molecular Formula	C11H13BrN2
Molecular Weight	253.14 g/mol
Synonyms	4-Bromo-2-tert-butyl-1H-pyrrolo[2,3-b]pyridine; 2-tert-Butyl-4-bromo-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-2-(tert-butyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-2-(1,1-dimethylethyl)-; 4-Bromo-2-(1,1-dimethylethyl)-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-2-tert-butyl-7-azaindole
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-2-(1,1-Dimethylethyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.