Description

7-Bromo-1,3-benzoxazole-2-thiol is a versatile heterocyclic building block featuring a bromine substituent and a thiol functional group. This compound is of significant value in organic synthesis and pharmaceutical research due to its dual reactivity, enabling both nucleophilic substitution and metal-catalyzed cross-coupling reactions. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand & Catalyst Development: The thiol group makes it a useful starting material for creating chelating ligands in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and photoactive materials.
• Chemical Biology Probes: Utilized to develop activity-based probes and labeling agents for studying enzyme function.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	7-Bromo-1,3-benzoxazole-2-thiol
CAS No.	1013643-09-8
Molecular Formula	C7H4BrNOS
Molecular Weight	230.08 g/mol
Synonyms	7-Bromo-2-mercaptobenzoxazole; 2-Benzoxazolethiol, 7-bromo-; 7-Bromo-2-benzoxazolethiol; 7-Bromo-2-mercapto-1,3-benzoxazole; 7-Bromobenzo[d]oxazole-2-thiol; 1013643-09-8; 7-Bromo-1,3-benzoxazole-2(3H)-thione (tautomer)
EINECS	Contact for details

Quality Control

Every batch of 7-Bromo-1,3-benzoxazole-2-thiol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.