Description

2,2,2-Trifluoro-1-Thiophen-2-Ylmethyl-Ethylamine is a high-value fluorinated amine building block featuring a thiophene heterocycle. This compound matters for its unique molecular architecture, which combines the electronic properties of fluorine and sulfur-containing rings, making it a critical intermediate in advanced synthesis. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by specialty chemical manufacturers developing functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl and thiophene groups can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers or additives for specialty polymers, coatings, or electronic materials.
• Chemical Biology Probes: Useful for labeling or modifying biomolecules in diagnostic and research applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	2,2,2-Trifluoro-1-Thiophen-2-Ylmethyl-Ethylamine
CAS No.	1012884-80-8
Molecular Formula	C8H10F3NS
Molecular Weight	209.23 g/mol
Synonyms	2,2,2-Trifluoro-1-(thiophen-2-ylmethyl)ethylamine; 1-(Thiophen-2-ylmethyl)-2,2,2-trifluoroethylamine; 2,2,2-Trifluoro-1-(2-thienylmethyl)ethylamine; α-(Trifluoromethyl)-2-thiopheneethanamine; 2-(Aminomethyl)-1,1,1-trifluoro-3-(2-thienyl)propane; TFTAE; Trifluoromethyl thiophene ethylamine; 1012884-80-8
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-Thiophen-2-Ylmethyl-Ethylamine undergoes rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) are available upon request for every batch, providing full traceability and supporting your quality management systems (ISO, GMP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong alkalis and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.