Description

n-Acetyl-Dl-Serine-15N is a stable isotope-labeled derivative of the amino acid serine, specifically enriched with nitrogen-15 at the indicated position. This compound is a critical tool for advanced research and development, enabling precise metabolic and proteomic studies through mass spectrometry and NMR spectroscopy. It is primarily utilized by pharmaceutical researchers, academic institutions, and diagnostic developers working in drug discovery, metabolic pathway analysis, and biomarker identification.

Application

• Isotopic Tracer in Metabolic Studies: Used to track and quantify nitrogen metabolism in biological systems, providing insights into protein synthesis and turnover rates.
• Internal Standard for Mass Spectrometry (MS): Essential for the accurate quantification of serine and related metabolites in complex biological samples via LC-MS or GC-MS.
• NMR Spectroscopy Reagent: Serves as a probe for structural and dynamic studies of proteins and peptides due to the distinct NMR signal of the 15N isotope.
• Pharmaceutical R&D: Employed in the development and testing of new therapeutic agents, particularly those targeting amino acid metabolism or requiring isotopic labeling.
• Nutritional and Biomedical Research: Facilitates studies on amino acid utilization, metabolic disorders, and the role of serine in cellular processes.
• Production of Labeled Peptides: Acts as a building block for the chemical synthesis of isotopically labeled peptides for use as standards or probes.

Basic Information

Product Name	n-Acetyl-Dl-Serine-15N
CAS No.	1012312-92-3
Molecular Formula	C5H915NO4
Molecular Weight	150.12 g/mol (for 15N labeled form)
Synonyms	N-Acetyl-DL-serine-15N; Acetylserine-15N; (RS)-2-Acetamido-3-hydroxypropanoic acid-15N; DL-2-(Acetylamino)-3-hydroxypropionic acid-15N; N-Acetyl-3-hydroxyalanine-15N; Stable Isotope Labeled N-Acetylserine; 15N Labeled N-Acetyl-DL-serine
EINECS	Contact for details

Quality Control

Every batch of n-Acetyl-Dl-Serine-15N is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure the highest standards of isotopic and chemical purity. Our quality assurance protocols are designed to meet the exacting requirements of research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA), detailing parameters such as isotopic enrichment, chemical purity, and identity confirmation, is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
15N Isotopic Enrichment	≥ 98 atom % 15N
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.