Description

6-Fluoro-3-Methyl-1H-Indole is a high-purity fluorinated indole derivative, a crucial building block in modern organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with tailored biological and physical properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where the introduction of fluorine atoms is a key strategy for modulating activity, stability, and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-inflammatory drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized organic molecules used in organic light-emitting diodes (OLEDs), semiconductors, and liquid crystals.
• Chemical Biology & Proteomics: Employed as a building block for fluorescent probes, enzyme inhibitors, and other biochemical tools.
• Academic & Contract Research: A valuable reagent for methodological development and synthetic chemistry studies in university and CRO laboratories.

Basic Information

Item	Detail
Product Name	6-Fluoro-3-Methyl-1H-Indole
CAS No.	1011484-23-3
Molecular Formula	C9H8FN
Molecular Weight	149.17 g/mol
Synonyms	3-Methyl-6-fluoroindole; 6-Fluoro-3-methylindole; 1H-Indole, 6-fluoro-3-methyl-; 6-Fluoro-3-methyl-1H-indole; FMI (abbreviation); 6-F-3-MI
EINECS	Contact for details

Quality Control

Every batch of 6-Fluoro-3-Methyl-1H-Indole is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistent lot-to-lot quality suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.