Description

4-Fluoro-3-Methyl-1H-Indole is a high-purity fluorinated indole derivative, a crucial building block in modern organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research institutions and industrial manufacturers focused on creating novel active ingredients, where its unique fluorine substitution pattern enables precise tuning of biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances metabolic stability and bioavailability.
• Material Science Research: Serves as a precursor for functionalized organic materials and specialty chemicals with tailored electronic properties.
• Academic & R&D Laboratories: Employed in methodological studies and as a standard in fluorination chemistry and heterocyclic compound synthesis.
• Fluorescent Probe Development: Potential use in the design of molecular probes and sensors due to the indole fluorophore structure.

Basic Information

Product Name	4-Fluoro-3-Methyl-1H-Indole
CAS No.	1011484-22-2
Molecular Formula	C9H8FN
Molecular Weight	149.17 g/mol
Synonyms	3-Methyl-4-fluoroindole; 4-Fluoro-3-methylindole; 1H-Indole, 4-fluoro-3-methyl-; 4-Fluoro-3-methyl-1H-indole; 3-Methyl-4-fluoro-1H-indole
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methyl-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and relevant ICH guidelines ensures material integrity for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.