Description

4-Methyl-2-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-5-yl](pyrrolidin-1-yl)methanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique thiazole and trifluoromethoxy-substituted aromatic structure. This compound is critical for research and development in medicinal chemistry, offering a versatile scaffold for the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical companies, biotechnology research firms, and academic institutions engaged in drug discovery programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly in the development of small molecule therapeutics.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties.
• Protease Inhibitor Development: Its structural features make it relevant for research into inhibitors targeting specific enzymes like proteases.
• Kinase Inhibitor Scaffold: Employed in the discovery and optimization of kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Utilized to create tool compounds for investigating biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied for custom synthesis projects requiring complex, fluorinated heterocyclic compounds.

Basic Information

Product Name	4-Methyl-2-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-5-yl](pyrrolidin-1-yl)methanone
CAS No.	1010908-45-8
Molecular Formula	C16H15F3N2O2S
Molecular Weight	356.36 g/mol
Synonyms	(4-Methyl-2-(4-(trifluoromethoxy)phenyl)thiazol-5-yl)(pyrrolidin-1-yl)methanone; 1-(4-Methyl-2-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-5-yl)-2-pyrrolidin-1-ylethanone; 1010908-45-8; 4-Methyl-2-(4-trifluoromethoxyphenyl)thiazole-5-carboxylic acid pyrrolidide; Pyrrolidin-1-yl(4-methyl-2-(4-(trifluoromethoxy)phenyl)thiazol-5-yl)methanone
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-5-yl](pyrrolidin-1-yl)methanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.