Description

Methyl 4,5-Dimethyl-2-({[2-(Morpholin-4-Yl)-4-Oxo-4,5-Dihydro-1,3-Thiazol-5-Yl]Acetyl}Amino)Thiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is of significant commercial importance due to its role as a key building block in modern medicinal chemistry, particularly for developing novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in the creation of new drug candidates, especially those targeting specific enzymatic pathways. The CAS number for this product is 1010903-43-1.

Application

This specialized intermediate serves critical functions in advanced chemical synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in oncology and anti-infective research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Integral to the process development and scale-up of new Active Pharmaceutical Ingredients (APIs) requiring complex heterocyclic architectures.
• Biochemical Probe Synthesis: Employed in creating specialized molecules for investigating biological mechanisms and target validation.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical industry.

Basic Information

Product Name	Methyl 4,5-Dimethyl-2-({[2-(Morpholin-4-Yl)-4-Oxo-4,5-Dihydro-1,3-Thiazol-5-Yl]Acetyl}Amino)Thiophene-3-Carboxylate
CAS No.	1010903-43-1
Molecular Formula	C18H23N3O5S2
Molecular Weight	425.52 g/mol
Synonyms	Methyl 4,5-dimethyl-2-[[2-(4-morpholinyl)-4-oxo-5-thiazolidinyl]acetamido]-3-thiophenecarboxylate; 4,5-Dimethyl-2-({[2-(morpholin-4-yl)-4-oxo-4,5-dihydro-1,3-thiazol-5-yl]acetyl}amino)thiophene-3-carboxylic acid methyl ester; 1010903-43-1; Thiophene-3-carboxylic acid, 4,5-dimethyl-2-[[2-(4-morpholinyl)-4-oxo-5-thiazolidinyl]acetamido]-, methyl ester; AKOS025247193; Morpholine-thiazolidinone-thiophene carboxylate derivative; CS-0446645
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.