Description

1-{4-[(6-Bromo-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)Sulfonyl]Phenyl}Pyrrolidin-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating bromo, sulfonyl, and pyrrolidinone moieties. This compound is of significant value for its role as a key building block in the research and development of novel bioactive molecules, particularly in central nervous system (CNS) and oncology therapeutic areas. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing complex, target-specific drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening (HTS) campaigns to identify new lead structures.
• Biochemical Tool Compound: Employed in academic and industrial research to study specific biological pathways and protein-ligand interactions.
• Process Development & Scale-up: Utilized in optimizing synthetic routes from milligram to kilogram scale for preclinical and early-phase clinical material production.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in API (Active Pharmaceutical Ingredient) manufacturing.

Basic Information

Product Name	1-{4-[(6-Bromo-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)Sulfonyl]Phenyl}Pyrrolidin-2-One
CAS No.	1010885-32-1
Molecular Formula	C21H20BrN3O3S
Molecular Weight	474.37 g/mol
Synonyms	6-Bromo-2-{[4-(2-oxopyrrolidin-1-yl)phenyl]sulfonyl}-1,2,3,4,5,6-hexahydropyrido[4,3-b]indole; 1-[4-[(6-Bromo-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)sulfonyl]phenyl]pyrrolidin-2-one; UNII-2Q3C8F3W1K; 2Q3C8F3W1K; Pyrrolidin-2-one, 1-[4-[(6-bromo-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)sulfonyl]phenyl]-; BDBM50191057; HY-101088; ZINC000000899949
EINECS	Contact for details

Quality Control

Our 1-{4-[(6-Bromo-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)Sulfonyl]Phenyl}Pyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities to meet the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.