Description

Methyl n-{[1-(1H-Indol-2-Ylcarbonyl)Piperidin-3-Yl]Carbonyl}Glycinate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex bioactive molecules. This compound is critical for research and development in medicinal chemistry, particularly in constructing novel heterocyclic scaffolds. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, including kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting specific enzymes or receptors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic compounds.
• Protease & Kinase Inhibitor Development: Serves as a core structural component in the design of potential inhibitors for various disease pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Can be utilized in biochemical assays to study enzyme function and cellular signaling mechanisms.
• Academic & Institutional Research: Employed in university and institutional labs for exploratory research in organic and bioorganic chemistry.

Basic Information

Product Name	Methyl n-{[1-(1H-Indol-2-Ylcarbonyl)Piperidin-3-Yl]Carbonyl}Glycinate
CAS No.	1010884-52-2
Molecular Formula	C19H21N3O4
Molecular Weight	355.39 g/mol
Synonyms	Methyl N-[(1-[(1H-indol-2-yl)carbonyl]-3-piperidinyl)carbonyl]glycinate; Glycine, N-[(1-[(1H-indol-2-yl)carbonyl]-3-piperidinyl)carbonyl]-, methyl ester; Methyl 2-((1-(1H-indole-2-carbonyl)piperidin-3-yl)carbamoyl)acetate; (1H-Indole-2-carbonyl)-piperidine-3-carboxylic acid glycine methyl ester adduct; 1010884-52-2; Methyl 2-[[1-(1H-indole-2-carbonyl)-3-piperidyl]formamido]acetate
EINECS	Contact for details

Quality Control

Our Methyl n-{[1-(1H-Indol-2-Ylcarbonyl)Piperidin-3-Yl]Carbonyl}Glycinate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.